Principal Clinical Scientist

Principal Clinical Scientist (AI Training)About The Role What if your deep expertise in clinical trial design and regulatory science could directly influence how AI understands and evaluates clinical evidence for millions of patients worldwide? We're looking for a Principal Clinical Scientist to bring senior-level rigor to the AI systems being built by the world's leading research labs. This is a fully remote, flexible contract role designed for experienced clinical scientists who want to apply their expertise at the cutting edge of AI development. Your work will help ensure that AI models reason about clinical data the way a seasoned regulatory expert would — accurately, rigorously, and with real-world consequence.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
• Provide expert, structured feedback to improve how AI models reason about clinical trial data, outcomes, and evidence hierarchies
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold data to the highest scientific standard
• Clear, structured written communicator who can translate complex findings into actionable feedback

Nice to Have

• Prior experience with data annotation, data quality evaluation, or AI output review
• Background in pharmacovigilance, medical writing, or health technology assessment
• Familiarity with AI tools or scientific evaluation workflows
• Experience working across multiple therapeutic areas or regulatory jurisdictions

Why Join Us

• Work directly on frontier AI systems that are shaping the future of clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Make a direct, tangible impact on how AI understands and evaluates real-world clinical evidence
• Collaborate with world-class AI research teams and labs on genuinely novel problems
• Potential for ongoing work and contract extension as new projects launch